Witryna8 lip 2024 · Epigenetic-miRNAs regulatory networks have also been described in breast cancer. For instance, the miR-129-2 gene has been observed to be hypermethylated in breast cancer. Furthermore, downregulation of miR-129-2 by promoter hypermethylation has been shown to regulate cell proliferation and apoptosis . ... WitrynaMicroRNAs (miRNAs) are small noncoding RNAs, approximately 18-25 nucleotides in length, now recognized as one of the major regulatory gene families in eukaryotes. Recent advances have been made in understanding the complicated roles of miRNAs …
MicroRNAs — new biomarkers of respiratory tract diseases
Witryna13 kwi 2024 · Breast cancer exhibits various epigenetic abnormalities that regulate gene expression and contribute to tumor characteristics. Epigenetic alterations play a significant role in cancer development and progression, and epigenetic-targeting drugs such as DNA methyltransferase inhibitors, histone-modifying enzymes, and mRNA … WitrynaMicroRNAs (miRNAs) are part of the epigenetic mechanisms that regulate gene expression at a post-transcriptional level. This review describes some miRNAs whose expression is modified in obesity and that may be involved in the development of insulin resistance. The metabolic alterations associated with obesity are due to an adipose … im ready fir a permanent host on jeopardy
Functions and mechanisms of epigenetic inheritance in animals
WitrynaMicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene expression post-transcriptionally. Recent studies have demonstrated that epigenetic … Witryna13 lis 2024 · In this Review, we explore the principles of meiotic epigenetic inheritance (MEI) in animals, which we define as epigenetic inheritance through meiotic products that spans at least two... WitrynaMicroRNAs (miRNAs) represent a group of small, non-coding RNA molecules that have been shown to regulate gene expression at the translational level by interfering with the 3’ untranslated region of messenger RNAs. Gene silencing through miRNA interference is one epigenetic mechanism impacting the development and homeostasis of the … im ready for promotion